产品详情 |
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Antigenic Specificity | beta Catenin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ChIP assay: Assay-Dependent, Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Immunoprecipitation: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | beta Catenin Polyclonal Antibody. Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The interpla |
Immunogen | n/a |
Other Names | CTNNB, DKFZp686D02253, FLJ25606, FLJ37923, CTNNB1, catenin beta-1, catenin (cadherin-associated protein), beta 1, 88kDa |
Gene, Accession # | Entrez: 12387, 1499, 84353; Uniprot: P35222, Q02248, Q9WU82 |
Catalog # | PA5-77934 |
Price | |
Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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