产品详情 |
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Antigenic Specificity | beta Catenin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chicken, human, mouse, rat, Xenopus laevis |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.1-1 mg/mL, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:20-1:200, Immunoprecipitation: 5-10 µg, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | beta Catenin Polyclonal Antibody (CAT-15). Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The |
Immunogen | n/a |
Other Names | CATNB, CTNB1, CTNNB, catenin, beta |
Gene, Accession # | Entrez: 12387, 1499, 395964, 399274, 84353; Uniprot: P26233, P35222, Q02248, Q9WU82 |
Catalog # | 71-2700 |
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Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12533412, 12791303, 15147582, 15880438, 15882576, 18201716, 19224982, 19720156, 20212454, 20396778, 21256972, 21471187, 21685894, 22252313, 22522917, 22670221, 22797892, 22872576, 22875787, 23097088, 23169788, 23248771, 23565266, 24169556, 25217631, 25717188, 25777294, 25873562, 25976454, 26048141, 26879129, 26888480, 26905250, 27179130, 27358069, 27411103, 27559491, 27815338, 28954226 |
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