产品详情 |
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Antigenic Specificity | beta Catenin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | canine, feline, goat, human, mouse, nonhuman primate, ovine, porcine, rat, rodent, Xenopus laevis, zebrafish |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.1 µg/mL, Immunocytochemistry: 1-5 µg/mL, Immunofluorescence: 1-5 µg/mL, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 0.5-1 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 0.25 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | beta Catenin Polyclonal Antibody. Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The interpla |
Immunogen | n/a |
Other Names | OK/SW-cl.35, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923, catenin beta-1 |
Gene, Accession # | Entrez: 12387, 1499, 30265, 399274, 84353; Uniprot: P26233, P35222, Q02248, Q9WU82 |
Catalog # | PA5-19469 |
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Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26752347, 27086928, 29042773 |
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