产品详情 |
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Antigenic Specificity | beta Catenin |
Clone | CAT-5H10 |
Host Species | Mouse |
Reactive Species | chicken, human, mouse |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | beta Catenin Monoclonal Antibody (CAT-5H10). Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. T |
Immunogen | n/a |
Other Names | CATNB, CTNB1, CTNNB, catenin, beta |
Gene, Accession # | Entrez: 12387, 1499, 395964; Uniprot: P35222, Q02248 |
Catalog # | 13-8400 |
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Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10506713, 10652321, 10722635, 10898731, 10923074, 11212238, 11328805, 11391575, 11533074, 11547897, 11923426, 11950839, 12393869, 12557145, 12640032, 12822869, 14722018, 14744872, 15128072, 15144953, 15188132, 15216416, 15262114, 15365368, 15378486, 15568158, 15623481, 15723280, 15838877, 15851108, 16036634, 16483002, 16835298, 16941013, 17199044, 17210688, 17504299, 17576040, 17577324, 17623804, 17631398, 18031986, 18181141, 18183411, 18193278, 18254773, 18609711, 19019843, 19201419, 19823059, 20427117, 20732910, 21245375, 21518380, 21521738, 21621589, 21715983, 21878227, 21975646, 22175900, 22684283, 22946055, 23027535, 23097141, 23155232, 23261932, 23332924, 23409082, 23548313, 23554857, 23580256, 23706092, 23714252, 23794494, 24062361, 24291548, 24511741, 24653638, 24950983, 25159326, 25175346, 25401518, 25456071, 25574191, 25590413, 25729345, 26005854, 26026096, 26453937, 26785729, 26967387, 26990065, 27009203, 27020567, 27155731, 27436542, 27447751, 27525003, 27774068, 27858992, 28296140, 28614798, 9501208 |
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