| 产品详情 |
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| Antigenic Specificity | ABCC5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABCC5 Antibody is a Rabbit Polyclonal antibody against ABCC5. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. |
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| Immunogen | A synthetic peptide of human ABCC5. |
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| Other Names | MRP5; SMRP; ABC33; MOATC; MOAT-C; pABC11; EST277145 |
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| Gene, Accession # | ABCC5, Gene ID: 10057, SwissProt: O15440 |
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| Catalog # | abx002191 |
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| Price | |
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| Order / More Info | ABCC5 Antibody from ABBEXA |
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| Product Specific References | n/a |
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