产品详情 |
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Antigenic Specificity | CCAR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCAR1 Polyclonal Antibody. CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. CCAR1 functions as a p53 coactivator, may play an important role in transcriptional regulation. CCAR1 may also be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. CCAR1 plays a role in cell |
Immunogen | n/a |
Other Names | RP11-437A18.1, cell division cycle and apoptosis regulator 1 |
Gene, Accession # | Entrez: 55749, 67500; Uniprot: Q8CH18, Q8IX12 |
Catalog # | PA5-78532 |
Price | |
Order / More Info | CCAR1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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