α-Amino-2,3-dihydro-4-methoxy-7-
nitro-δ-oxo-1H-indole-1-pentanoic acid
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Biological Activity MNI-caged glutamate that rapidly nd efficiently releases (Cat.No. 0218) when photolysed (300 - 380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate. Licensing Information Sold under license from the Medical Research Council Technical Data 323.3 C14Hsub>17N3O6 Soluble to 50 mM in water >98 % Store at -20°C [295325-62-1] The technical data provided above is for guidance only. Resources
<3>Certificate of Analysis / MSDS Certificate of Analysis: Select another batch: 31302928272625242322212019181716151413121110987654321 Material Safety Data Sheet: View current batch> Select another batch: 31302928272625242322212019181716151413121110987654321 References Papageorgiouand Corrie (2000)Effects of aromatic substitutions on the photocleavage of1-acyl-7-nitroindolines. Tetrahedron 56 8197. Canepari etal (2001) Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast cagedneurotransmitters. J.Neurosci.Methods 112 29. Matsuzaki etal (2001) Dendritic spine geometry is critical for AMPA receptor expressionin hippocapal CA1 pyramidal neurons. Nature Neurosci. 4 1086. Maieret al (2005) Comparative analysisof inhibitory effects of cged ligandsfor the NMDA receptor. J.Neurosci.Meths. 142 1. If you know of a useful citation for this product . |