Phospho-p53 (Ser15) Antibody detects endogenous levels of p53 only when phosphorylated at Serine 15. Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy.
| Target |
p53 (pS15) |
| Reactivity |
Human, Rat |
| Host |
Rabbit |
| Modification |
Phosphorylation |
| Target Modification |
Ser15 |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P04637
|
| GeneID |
7157
|
| Gene Symbol |
TP53 |
| OMIM |
191170
|
| HGNC |
11998 |
| Ensembl |
ENSG00000141510 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |