NBN Antibody is a Rabbit Polyclonal antibody against NBN. Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
| Target |
NBN |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IF/ICC, FCM |
| Recommended dilutions |
WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
A synthetic peptide of human NBN. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 84 kDa
Observed MW: 105 kDa |
| Swiss Prot |
O60934
|
| GeneID |
4683
|
| Gene Symbol |
NBN |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |