Phospho-Akt1 (Thr450) Antibody detects endogenous levels of Akt1 only when phosphorylated at Threonine 450. an AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway.
| Target |
Akt1 (pT450) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P31749
|
| GeneID |
207
|
| Gene Symbol |
AKT1 |
| OMIM |
164730
|
| Enzyme Commission Number |
EC 2.7.11.1 |
| HGNC |
391 |
| Ensembl |
ENSG00000142208 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |