Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters.The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis.Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia.Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart.Highest levels in thymus, bone marrow and peripheral blood.
| Target |
RUNX1 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, IF/ICC |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthesized peptide of human RUNX1. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
55 kDa |
| Swiss Prot |
Q01196
|
| GeneID |
861
|
| Gene Symbol |
RUNX1 |
| OMIM |
151385
|
| HGNC |
10471 |
| Ensembl |
ENSG00000159216 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |