产品名称 Serum Paraoxonase / Arylesterase 1 (PON1) Antibody
产品货号 Catalogue No: abx001187
产品价格 现货询价,电话:010-67529703
产品规格 Available Options * Size: 100 µl 200 µl
产品品牌 abbexa
产品概述
产品详情
PON1 Antibody is a Rabbit Polyclonal antibody against PON1. Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.
Target PON1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, FCM
Recommended dilutions WB: 1/200 - 1/500, IHC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen A synthetic peptide of human PON1.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at 2°C to 8°C upon receipt.
Molecular Weight Calculated MW: 39 kDa
Observed MW: 40 kDa
Swiss Prot P27169
GeneID 5444
Gene Symbol PON1
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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