SRF Antibody is a Rabbit Polyclonal antibody against SRF. Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF is required for cardiac differentiation and maturation due to the role in cardiac cell growth and muscle gene regulation. Four alternatively spliced transcript variants encoding distinct isoforms (40,52,57,67 kDa) have been found for this gene (PMID:11893590).

Target	SRF
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC, IP
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human SRF.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 51 kDa Observed MW: 60 kDa
Swiss Prot	P11831
GeneID	6722
Gene Symbol	SRF
Concentration	> 1 mg/ml
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.