SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Target |
SOX2 |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
ELISA, WB |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli. |
Purification |
Unpurified Ascites. |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
34.3 kDa |
Swiss Prot |
P48431
|
GeneID |
6657
|
Gene Symbol |
SOX2 |
OMIM |
184429
|
HGNC |
11195 |
Ensembl |
ENSG00000181449 |
Buffer |
Ascitic fluid containing 0.03% sodium azide. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |