产品名称 Sestrin 1 (SESN1) Antibody
产品货号 Catalogue No: abx002451
产品价格 现货询价,电话:010-67529703
产品规格 Available Options * Size: 100 µl 200 µl
产品品牌 abbexa
产品概述
产品详情
SESN1 Antibody is a Rabbit Polyclonal antibody against SESN1. This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Target SESN1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications WB, FCM
Recommended dilutions WB: 1/500 - 1/2000, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human SESN1.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at 2°C to 8°C upon receipt.
Molecular Weight Calculated MW: 49 kDa/56 kDa/63 kDa
Observed MW: 65 kDa
Swiss Prot Q9Y6P5
GeneID 27244
Gene Symbol SESN1
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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