The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Target |
SOX9 |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
ELISA, WB, IF/ICC |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified recombinant fragment of human SOX9 expressed in E. Coli. |
Purification |
Purified antibody |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
56 kDa |
Swiss Prot |
P48436
|
GeneID |
6662
|
Gene Symbol |
SOX9 |
OMIM |
608160
|
HGNC |
11204 |
Ensembl |
ENSG00000125398 |
Concentration |
1.0 mg/ml |
Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |