This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome);.
Target |
SRY |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
ELISA, WB, IHC, FCM |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified recombinant fragment of human SRY (AA:1-204) expressed in E. Coli. |
Purification |
Purified antibody |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
23.9 kDa |
Swiss Prot |
Q05066
|
GeneID |
6736
|
Gene Symbol |
SRY |
OMIM |
480000
|
HGNC |
11311 |
Ensembl |
ENSG00000184895 |
Concentration |
1.0 mg/ml |
Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |