SH2D1A Antibody is a Rabbit Polyclonal antibody against SH2D1A. SH2D1A and SH2D1B are small, adaptor proteins with a single SH2-domain that play important signal transduction roles mediated by the signaling lymphocytic activation molecule (SLAM) family receptorsSH2D1A (also called SAP or SLAM-associated protein) is frequently mutated in patients with X-linked lymphoprolifeRative disease (Duncan’s disease), which is characterized by extreme susceptibility to Epstein-Barr virus; approximately 50 different SH2D1A mutations have been reported to dateThe single SH2D1B gene in humans (also called EAT-2 or Ewings sarcomas/FLI1-activated transcript 2) is present as a pair of duplicated EAT-2A and EAT-2B genes with identical genomic organization in mouse and Rat.
Target |
SH2D1A |
Reactivity |
Human, Mouse, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
ELISA, WB, IHC |
Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant protein of human SH2D1A. |
Purification |
Affinity Chromatography. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
O60880
|
GeneID |
4068
|
Gene Symbol |
SH2D1A |
Buffer |
PBS, pH7.3, containing 0.02% sodium azide and 50% Glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |