Phospho-SHP2 (Tyr580) Antibody detects endogenous levels of SHP2 only when phosphorylated at Tyrosine 580. SHP2 a SH2-containing a ubiquitously expressed tyrosine-specific protein phosphatase. It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens and extracellular matrices in the control of cell growth, differentiation, migration, and death.
Target |
SHP2 (pY580) |
Reactivity |
Human, Mouse, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB |
Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
Purification |
Purified by affinity chromatography. |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
Q06124
|
GeneID |
5781
|
Gene Symbol |
PTPN11 |
OMIM |
176876
|
HGNC |
9644 |
Ensembl |
ENSG00000179295 |
Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |