产品名称 Signal Transducer CD24 (CD24) Antibody (APC)
产品货号 Catalogue No: abx200194
产品价格 现货询价,电话:010-67529703
产品规格 Available Options * Size: 100 tests
产品品牌 abbexa
产品概述
产品详情
The monoclonal antibody is directed against the CD24- antigen, which is expressed on virtually all B-cells: early B-cell precursors, pre-pre-B-cells, pre-B-cells, B- cells, intermediate B-cells, mature B-cells and some plasmacytoid cells are positive while plasmacells are negative. The monoclonal antibody reacts with human granulocytes and their precursors (from promyelocytic stage). The monoclonal antibody also reacts with virtually all pre-B-cell lines and Burkitt cell lines, but is only expressed on less then 50% of the B-cell lymphoblastoid cell lines. Non T-ALL, B-cell NHL and 50% of myelomas as well as a subpopulation of AML is found to be positive. Hairy Cell Leukaemia is found to be weakly positive.
Target CD24
Reactivity Human
Host Mouse
Clonality Monoclonal
Tested Applications FCM
Recommended dilutions FCM: 20 µl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Glycoproteins purified from human NALM-1 cell line.
Purification Affinity Chromatography
Form Liquid
Isotype IgG1
Conjugation APC
Specificity The antibody reacts with the CD24 antigen a heavily glycosylated molecule that migrates as a broad band of 35-45 kDa on both reducing and non-reducing SDS gel electrophoresis. CD24 is attached to the cell membrane via a glycosyl phosphatidylinositol (GPI) anchor and is expressed at multiple stages of B cell development, beginning with the bone marrow CD34 positive pro-B cell compartment and continuing through mature surface IgM positive/IgD positive B cells. CD24 is also expressed on the vast majority of B-lineage acute lymphoblastic leukaemias, B cell chronic lymphocytic leukaemias and B cell non-Hodgkin's lymphoma. In the normal spleen, mantle zone lymphocytes are CD24 strongly positive, but germinal center cells are CD24 negative or CD24 weakly positive
Storage Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.
Molecular Weight 35-45 kDa
Swiss Prot P25063
GeneID 100133941
Buffer The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
UNSPSC Code 12352203
Availability Shipped within 3-5 working days.
Note This product is for research use only.
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