产品名称 Signal Transducer And Activator of Transcription 6 (STAT6) Antibody
产品货号 Catalogue No: abx000847
产品价格 现货询价,电话:010-67529703
产品规格 Available Options * Size: 50 µl 100 µl 200 µl
产品品牌 abbexa
产品概述
产品详情
STAT6 Antibody is a Rabbit Polyclonal antibody against STAT6. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
Target STAT6
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human STAT6.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 74 kDa/81 kDa/94 kDa
Observed MW: 80 kDa
Swiss Prot P42226
GeneID 6778
Gene Symbol STAT6
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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