STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation.STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta.STAT6 is critically involved in Th2 immune response.
Target |
STAT6 |
Reactivity |
Human, Mouse, Rat, Monkey |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
ELISA, WB, IF/ICC |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified recombinant fragment of human STAT6 expressed in E. coli. |
Purification |
Unpurified Ascites. |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
94 kDa |
GeneID |
6778
|
Buffer |
Ascitic fluid containing 0.03% sodium azide. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |