产品名称Capsaicin
产品货号M2028
产品价格现货询价,电话:010-67529703
产品规格M2028
产品品牌sigmaaldrich
产品详情

Description

Packaging

1 g in glass bottle

250 mg in glass bottle

50 mg in poly bottle

Application

Capsaicin has been used:
• to study its effects on chromatin remodeling and gene expression related to synaptic plasticity
• to study TRPV1 channel signaling in H2C1 cells (which are human embryonic kidney 293 cells expressing TRPV1 channels)

Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

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