PRODUCT NUMBER:

MW: 37,000**
**Azurocidin is highly glycosylated, which causes the protein to show a lower molecular weight by SDS-PAGE than that stated of 37kDa.
Extinction Coefficient: 0.51

Salt-free lyophilized solid.

Storage: -20°C

Buy Purified Native Human Azurocidin, Human Neutrophil (Cationic Protein 37)
Bulk Qty Available.

The gene for azurocidin is located on the short arm of chromosome 19 and is in a cluster with the genes for proteinase 3 and elastase. All three proteins are serine protease homologues; azurocidin, however, lacks enzymatic activity. The importance of azurocidin is its role as a multifunctional inflammatory mediator. It has antimicrobial activity, binds endotoxin and is chemotactic for monocytes.

Purity: >=95% by SDS-PAGE

Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Product Citation:

Zimmer M, Medcalf RL, Fink TM, Mattman C, Lichter P, and Jenne DE. 1992. Proc. Natl. Acad. Sci. USA 89, 8215. Pereira HA. 1995. J Leukoc Biol. 57, 805.

O'Flynn, J., K. O. Dixon, Faber Krol, M. R. Daha, and C. van Kooten. "Myeloperoxidase Directs Properdin-Mediated Complement Activation." Journal of Innate Immunity (2013).

Brandt K, Grunler J, Brismar K, Wang J
Effects of IGFBP-1 and IGFBP-2 and their fragments on migration and IGF-induced proliferation of human dermal fibroblasts.
Growth Horm IGF Res. 2015 Feb;25(1):34-40. doi: 10.1016/j.ghir.2014.11.001. Epub 2014 Nov 8.