PRODUCT NUMBER:

MW: 28,000
Extinction Coefficient: 1.22

Frozen in 20 mM Na Acetate, pH 4.5, with 1 mM EDTA and 100mM NaCl

Storage: -70°C or lower

Buy Purified Native Human Cathepsin H (CatH), Human Liver.
Bulk Qty Available.

A more basic protein than Cathepsin B or L. Functions as both an aminopeptidase and endopeptidase. Cathepsin H, like cathepsin L and B, is involved in the catabolism of proteins in the lysosomal system.

Activity: greater than 1 unit per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of L-arginine-beta-napthylamide per minute at 40oC using 75 mM potasium phosphate, pH 6.8, with 1 mM EDTA and 3 mM cysteine as the activation buffer.

Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.

Product Citation:
Douglas Lu, Weiya, Lydiane Funkelstein, Thomas Toneff, Thomas Reinheckel, Christoph Peters, and Vivian Hook. "Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters." Journal of neurochemistry 122, no. 3 (2012): 512-522.

Ref:
Barrett, A.J. and Kirschke, H. 1981. Methods Enzymol. 80, 535.
Barrett, A.J. 1977. Proteinases in Mammalian Cells and Tissues. (A. Barrett, ed.) 4, 209