产品说明
实时研究细胞之间的相互作用
cell-cell interactions in real-time
一种多器官/细胞类型的模块化“即插即用”共培养技术，可在标准的体外环境中模拟器官的微环境。该技术为研究人员提供了一种新颖的方法，可以更好地预测人类对新药，化妆品，食品和病毒的反应 。
该平台以标准孔板格式设计，使其与标准读数设备兼容。
CELLBLOKS®是一种多器官/细胞类型的模块化“即插即用”共培养技术。 它用于在标准体外环境中模拟器官微环境的目的。 通过使用标准灌注摇杆，它可以研究在2D，3D细胞生长条件以及静态或流动系统中进行测定的可行性，使用CELLBLOKS®，可以在Barrier Pod?或Circulatory Blocks?上生长不同的细胞类型，它们模仿屏障器官或系统循环的器官。 然后可以通过多种方式将包含器官特定细胞的模块彼此连接起来，以模拟复杂的
器官-器官相互作用。 例如，肠细胞在屏障块上生长，而肝和肺细胞在循环块上 。
轻松进行细胞间通讯研究CELLBLOKS®平台具有SBS标准组织培养孔板的尺寸。 它具有四个单du的细长通道，并且可以放置三个单du的模块。 每个通道都充满了介质（3-5毫升），以允许各个模块之间的细胞通信。
多细胞和器官型共培养
配置组合矩阵进行中的研究的多个细胞类型的相互作用
CELLBLOKS®系统允许您设置三向组合的可能性，这意味着系统中的多个细胞类型都可以在一个板中以两个或三个训练分别进行测试。可以，CELLBLOKS®是使研究 CELLBLOKS®矩阵使您能够识别和选择正确的细胞类型组合，从而在早期进行进一步研究，从而帮助您节省时间和资金。
快速简单的分析
实时可视化和监控
开放式访问允许您实时监控实验。可以通过标准共聚焦显微镜对细胞进行实时成像而不会被破坏。另外，当细胞相互作用时，可以收集培养基用于进一步分析，从而可以研究长期作用。
节省时间
易于设置的“即插即用”模块设计也便于实时修改实验。在不干扰培养中其他细胞的情况下，可随时从基室中取出并替换单个细胞生长阻滞物。这样一来，您就可以有更多时间来生成所需的数据，而从一开始就可以花费更少的时间来重置实验。
更具生产力
在一个平台上同时执行多个实验
每个平台都有四个单du的通道，可以在一台设备中同时运行单du的单元间交互实验，从而在更短的时间内实现更高的生产率。
再现性更高
通过在整个实验中维持相似的环境来产生可靠的数据
CELLBLOKS®以标准SBS平板格式设计，可与常规的CO2恒温箱和读数设备配合使用。这使您能够大程度地减少标准培养皿和读出设备之间的环境差异，从而为您提供更可靠和可重复的数据。
气密性减少污染，减少介质蒸发并避免pH漂移的更好方法CELLBLOKS®腔室具有新设计的“夹气式”“气密”功能，带有两个侧夹，可轻松在腔室周围形成100％的气密密封 。
盖子上装有PTFE空气过滤器和O形圈密封件，以过滤到达细胞培养物中的空气。 养殖中的气体只能通过选择性渗透的空气过滤器（0.2毫米）进行交换
这样可以减少细胞潜在的污染，培养基的蒸发以及实验过程中pH的波动。 与其他细胞培养平台相比，Air-Lid技术是shou创的
-实现更可重复的数据采集和处理优势
CELLBLOKS®, is a multi-organ/cell type modular “plug and play” co-culture technology. It serves the purpose of emulating the organ microenvironment in a standard in-vitrosetting. It provides the feasibility of studying the assays in 2-D, 3-D cell growth condition, and in static or flow system, by using a standard perfusion rocker
Using CELLBLOKS® different cell types can be grown on Barrier Blocks? or Circulatory Blocks? that emulate barrier organs or those in systematic circulation. Blocks containing organ specific cells can then be connected to each other in variety of ways to simulate complex organ-organ interactions. For instance, Intestinal cell are grown on Barrier Blocks, whereas Liver and lung cells in Circulatory Blocks.
In this way you can quickly and easy set up an experiment in the lab to simulate complex body conditions, for example, to test how organs communicate to each other when they are exposed to a test drug
THE PLATFORM
Cell-cell communication studies made easy
CELLBLOKS® platform has dimensions of a SBS standard Tissue Culture well plate. It has four sperate elongated channels with location for three separate Blocks. Each channel is filled with media (3-5 ml) to allow the cell-cell communication between the Blocks
THE CELL GROWTH BLOCKS
Achieve better representation of different Organtype communications
1. Circulatory Blocks? provide a flat plastic surface for cells to grow with side circulatory windows on the walls allowing selective media diffusion (both inlet and outlet, simulating organs in systematic circulation e.g. liver, brain, heart, lung).
2. Barrier Blocks? contain a selective permeable membrane on the bottom of the Block, allowing cell to proliferative on basolateral membrane (simulating epithelial cells and tissues).
3. Blank Blocks? have the same flat surface as the Circulatory Blocks for cell growth but no inlet or outlet for media diffusion. Blank Blocks are used to isolate cell cultures from other compartments and are often used as controls.
In addition, the modular nature of the device allows the removal of one or more cell growth Blocks from the chamber to perform separate analysis without disturbing others cell compartments in culture.
Furthermore, as it provides separate compartments for each cells of a co-culture that cross-communicate among each other through media without leaving their compartment (unlike the conventional co-culture models), this permits user to study individual biology of each cell (e.g. protein, imaging, DNA).
FILTERED AIR FLOW
Better ways to reduce contamination, media evaporation and avoid pH drifts
The CELLBLOKS® chamber comes with new design Clip-Closure "Air-Lid" feature with two side clips that make it easy to create 100% hermetic seal around the chamber.
PTFE air filters and an o-ring seal have been incorporated in the lid in order to filter the air reaching cell cultures. Gas is in cultures is only exchanged through selectively permeable air filters (0.2 micorn) which reduce potential contamination of cells, evaporation of media, and fluctuations of pH during experimentation. In contrast to other cell culure platforms the Air-Lid technology is first-of-its-kind - enabling more reproducible data acqusitions and handling advantages.
How do the molecules diffuse between the Blocks
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