TACI,肿瘤坏死因子受体超家族成员13B抗体
英文名称: Anti-TACI antibody
型号:null    抗体货号: HZ-4841R
价格:请致电:010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

TACI,肿瘤坏死因子受体超家族成员13B抗体

产品编号HZ-4841R
英文名称TACI
中文名称肿瘤坏死因子受体超家族成员13B抗体
别 名TACI; CD267; CD267 antigen; CVID; TNFRSF 13B; TNFRSF 14B;TNFRSF13B; TNFRSF13B protein; TNFRSF14B; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 淋巴细胞 t-淋巴细胞
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
TACI,肿瘤坏死因子受体超家族成员13B抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human TNFRSF13B/CD267/TACI
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
TACI,肿瘤坏死因子受体超家族成员13B抗体PubMedPubMed
产品介绍background:
TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

Subcellular Location:
Membrane; Single-pass type III membrane protein.

Tissue Specificity:
Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.

Similarity:
Contains 2 TNFR-Cys repeats.

Database links:
Entrez Gene: 23495 Human
Entrez Gene: 57916 Mouse
Omim: 604907 Human
SwissProt: O14836 Human
SwissProt: Q9ET35 Mouse
Unigene: 158341 Human
Unigene: 265915 Mouse

TACI,肿瘤坏死因子受体超家族成员13B抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.