SYNC,微管卷曲蛋白SYNC抗体

产品编号HZ-9463R
英文名称SYNC
中文名称微管卷曲蛋白SYNC抗体
别 名Intermediate filament protein syncoilin; SYNC; SYNC1; SYNCI_HUMAN; Syncoilin; Syncoilin intermediate filament 1; Syncoilin-1.
说 明 书0.1ml 0.2ml
研究领域神经生物学 信号转导 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
SYNC,微管卷曲蛋白SYNC抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SYNC/Syncoilin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SYNC,微管卷曲蛋白SYNC抗体PubMedPubMed
产品介绍background:
Syncoilin (SYNC) is a 483 amino acid member of the intermediate filament family. Localized to the perinuclear region of cytoplasm, Syncoilin interacts with Alpha-Dystrobrevin and Desmin. Syncoilin links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle, and is therefore found at high levels in cardiac and skeletal muscle. Syncoilin is upregulated at the sarcolemma in individuals with various forms of neuromuscular disease. The gene that encodes Syncoilin maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Subunit:
Interacts with DES and DTNA.

Subcellular Location:
Cytoplasm, perinuclear region.

Similarity:
Belongs to the intermediate filament family.

Database links:
UniProtKB/Swiss-Prot: Q9H7C4.3

SYNC,微管卷曲蛋白SYNC抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.