MYOM1,肌间蛋白1抗体

产品编号HZ-9863R
英文名称MYOM1
中文名称肌间蛋白1抗体
别 名190 kDa connectin-associated protein; 190 kDa titin-associated protein; EH myomesin; MGC134946; MGC134947; MYOM1; MYOM1_HUMAN; Myomesin 1 185kDa; Myomesin family member 1; Myomesin-1; Skelemin.
说 明 书0.1ml 0.2ml
研究领域心血管 发育生物学 干细胞 细胞骨架
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
MYOM1,肌间蛋白1抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量188kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human MYOM1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
MYOM1,肌间蛋白1抗体PubMedPubMed
产品介绍background:
Myomesin-1 and myomesin-2 are components of the vertebrate myofibrillar M band and are associated with Titin, Myosin and Connectin. The myomesin proteins are responsible for the formation of a head structure on one end of the Titin string that connects the Z and M bands of the sarcomere. Myomesin-1 and -2 have unique N-terminal domains and are expressed mainly in skeletal muscle. The gene encoding human myomesin-1 maps to chromosome 18p11.31-p11.32.

Function:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Subunit:
Interacts with TTN/titin (By similarity). Interacts with PNKD.

Tissue Specificity:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Similarity:
Contains 5 fibronectin type-III domains.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

Database links:
Entrez Gene: 8736 Human
Omim: 603508 Human
SwissProt: P52179 Human
Unigene: 464469 Human

MYOM1,肌间蛋白1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.