C10orf27,第10号染色体开放阅读框27抗体

产品编号HZ-9720R
英文名称C10orf27
中文名称第10号染色体开放阅读框27抗体
别 名C10orf27; chromosome 10 open reading frame 27; FLJ32820; Stromal protein associated with thymii and lymph node homolog; stromal protein associated with thymii and lymph nodes; TBATA_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
C10orf27,第10号染色体开放阅读框27抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量39kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human C10orf27/SPATIAL
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
C10orf27,第10号染色体开放阅读框27抗体PubMedPubMed
产品介绍background:
C10orf27, also known as spatial, is a 351 amino acid cytoplasmic protein belonging to the spatial family. C10orf27 is suggested to play a role in spermatid differentiation. Existing as two alternatively spliced isoforms, C10orf27 is widely expressed in multiple tissues, including brain, thymus and testis. C10orf27 may be associated with multiple sclerosis (MS) susceptibility and pathogenesis. MS is an inflammatory disease that causes gradual destruction of myelin in the central nervous system. C10orf27 is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

Function:
May play a role in spermatid differentiation (Bysimilarity). Modulates thymic stromal cell proliferation and thymusfunction (By similarity).

Subcellular Location:
Cytoplasm,

Similarity:
Belongs to the TBATA family.

Database links:
Entrez Gene: 219793 Human
Omim: 612640 Human
SwissProt: Q96M53 Human

C10orf27,第10号染色体开放阅读框27抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.