Neurotrimin,神经营养因子HNT抗体

产品编号HZ-11082R
英文名称Neurotrimin
中文名称神经营养因子HNT抗体
别 名hNT; HNT; IgLON family member 2; IGLON2; Neurotrimin; NT antibody NTM; NTRI_HUMAN.
说 明 书0.1ml 0.2ml
研究领域神经生物学 生长因子和*** 细胞粘附分子 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
Neurotrimin,神经营养因子HNT抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Neurotrimin/HNT
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Neurotrimin,神经营养因子HNT抗体PubMedPubMed
产品介绍background:
Cell adhesion molecules (CAMs) influence cell growth, differentiation, embryogenesis, immune response and cancer metastasis by networking information from the extracellular matrix to the cell. The four major families of cell adhesion molecules are immunoglobulin (Ig) superfamily (calcium-independent transmembrane glycoproteins), integrins (transmembrane non-covalently linked heterodimers of Alpha and Beta subunits), calcium-dependent cadherins and divalent cation-dependent selectins. Regulation of neuronal synaptic adhesion by CAMs has proven important for learning and memory. Proper embryonic morphogenic development is also heavily dependent on the regulation of cell adhesion molecules. Neurotrimin (hNT) is a neural cell adhesion molecule localizing to the cell membrane, where it acts as a lipid-anchor. Neurotrimin belongs to the IgLON family of proteins, a member of the larger immunoglobulin superfamily.

Function:
Neural cell adhesion molecule.

Subunit:
Belongs to the immunoglobulin superfamily. IgLON family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

Subcellular Location:
Cell membrane.

Neurotrimin,神经营养因子HNT抗体Similarity:
Belongs to the immunoglobulin superfamily. IgLON family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

Database links:
Entrez Gene: 50863 Human
Omim: 607938 Human
SwissProt: Q9P121 Human
Unigene: 504352 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.