COX6A2,细胞色素C氧化酶蛋白6A2抗体

产品编号HZ-14008R
英文名称COX6A2
中文名称细胞色素C氧化酶蛋白6A2抗体
别 名COX VIa M; COX6AH; COXVIAH; Cytochrome c oxidase polypeptide VIa heart; Cytochrome c oxidase subunit 6A2 mitochondrial; Cytochrome c oxidase subunit VIA muscle; Cytochrome c oxidase subunit VIa polypeptide 2; MS411.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 新陈代谢 线粒体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Horse, Rabbit,
COX6A2,细胞色素C氧化酶蛋白6A2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量9.6kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human COX6A2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
COX6A2,细胞色素C氧化酶蛋白6A2抗体PubMedPubMed
产品介绍background:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008]

Function:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. COX is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. COX6A2 is polypeptide 2 of subunit VIa, and is present only in striated muscles. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex.

Subcellular Location:
Mitochondrion inner membrane

Tissue Specificity:
Expressed specifically in heart and muscle.

Similarity:
Belongs to the cytochrome c oxidase subunit 6A family.

Gene ID:
1339

COX6A2,细胞色素C氧化酶蛋白6A2抗体Database links:
Entrez Gene: 1339 Human
Entrez Gene: 12862 Mouse
Omim: 602009 Human
SwissProt: Q02221 Human
SwissProt: P43023 Mouse
Unigene: 250760 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.