KLHL31,Kelch样蛋白31抗体

产品编号HZ-8057R
英文名称KLHL31
中文名称Kelch样蛋白31抗体
别 名KLHL; BKLHD6; BTB and kelch domain containing protein 6; KBTBD1; Kelch like protein 31; Kelch like protein KLHL; Kelch repeat and BTB domain containing protein 1; KLH31_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Zebrafish,
KLHL31,Kelch样蛋白31抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量70kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human KLHL31
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
KLHL31,Kelch样蛋白31抗体PubMedPubMed
产品介绍Function:
Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).

Tissue Specificity:
Strongly expressed in skeletal muscle and weakly in heart. According to PubMed:15302408, not expressed in other tissues. According to PubMed:18719355, abundantly expressed in both embryonic skeletal and heart tissues.

Post-translational modifications:
N-terminus is methylated by METTL11A/NTM1 (By similarity).

Similarity:
Contains 1 BACK (BTB/Kelch associated) domain.
Contains 1 BTB (POZ) domain.
Contains 6 Kelch repeats.

Database links:
UniProtKB/Swiss-Prot: Q9H511.1

KLHL31,Kelch样蛋白31抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.