phospho-ETS2 (Thr72),***酸化癌基因ETS2抗体

产品编号HZ-14175R
英文名称phospho-ETS2 (Thr72)
中文名称***酸化癌基因ETS2抗体
别 名ETS2 (phospho T72); p-ETS2 (phospho T72); ets 2 protein; ETS2; ETS2_HUMAN; ETS2IT1; Oncogene ETS2; Protein C-ets-2; v ets avian erythroblastosis virus E2 oncogene homolog 2; V ets erythroblastosis virus E26 oncogene homolog 2.
说 明 书0.1ml
产品类型***酸化抗体
研究领域肿瘤 细胞生物 信号转导 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Sheep,
phospho-ETS2 (Thr72),***酸化癌基因ETS2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量70kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human ETS2 around the phosphorylation site of Thr72
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
phospho-ETS2 (Thr72),***酸化癌基因ETS2抗体PubMedPubMed
产品介绍background:
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Function:
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.

Subcellular Location:
Nucleus.

Tissue Specificity:

Post-translational modifications:

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.

Gene ID:
2114

phospho-ETS2 (Thr72),***酸化癌基因ETS2抗体Database links:
Entrez Gene: 2114 Human
Entrez Gene: 23872 Mouse
Entrez Gene: 304063 Rat
Omim: 164740 Human
SwissProt: P15036 Human
SwissProt: P15037 Mouse
Unigene: 644231 Human
Unigene: 290207 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Paraformaldehyde-fixed, paraffin embedded (mouse placenta); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ETS2 (Thr72)) Polyclonal Antibody, Unconjugated (HZ-14175R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.