BTBD15,锌指蛋白851抗体

产品编号HZ-12908R
英文名称BTBD15
中文名称锌指蛋白851抗体
别 名BTB (POZ) domain containing 15; BTB/POZ domain-containing protein 15; BTBD15; HSPC063; MGC26123; MGC57431; MGC60348; MGC88058; OTTHUMP00000230934; OTTHUMP00000230935; OTTHUMP00000230937; OTTHUMP00000230938; ZBT44_HUMAN; Zbtb44; Zinc finger and BTB domain containing 44; Zinc finger and BTB domain-containing protein 44; Zinc finger protein 851; HSPC063; ZNF851; ZBTB44.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
BTBD15,锌指蛋白851抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量64kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ZBTB44
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BTBD15,锌指蛋白851抗体PubMedPubMed
产品介绍background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying protein. ZBTB44 is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Post-translational modifications:
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 4 C2H2-type zinc fingers.

BTBD15,锌指蛋白851抗体Database links:
Entrez Gene: 29068 Human
SwissProt: Q8NCP5 Human
Unigene: 178499 Human
Unigene: 728154 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.