Calcitonin,降钙素抗体

产品编号HZ-2174R
英文名称Calcitonin
中文名称降钙素抗体
别 名Alpha CGRP; alpha type CGRP; CALC 1; CALC A; CALC1; CALC1; CALCA; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP1; CGRP1; CGRPI; CT; CT; Katacalcin; KC; KC; CALC_HUMAN; MGC126648; calcitonin isoform CT preproprotein.
说 明 书0.1ml 0.2ml
研究领域肿瘤 信号转导 生长因子和*** 肿瘤细胞生物标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
Calcitonin,降钙素抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量3kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Calcitonin(85-117/141).
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Calcitonin,降钙素抗体PubMedPubMed
产品介绍background:
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Function:
Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

Subcellular Location:
Secreted.

Similarity:
Belongs to the calcitonin family.

Gene ID:
796

Calcitonin,降钙素抗体Database links:
Entrez Gene: 796 Human
Entrez Gene: 12310 Mouse
Entrez Gene: 24241 Rat
Omim: 114130 Human
SwissProt: P01258 Human
SwissProt: P70160 Mouse
SwissProt: P01257 Rat
SwissProt: P01261 Sheep
Unigene: 37058 Human
Unigene: 90085 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.