ISOPORE POLYCARB .4UM BK PL 25MM 100/PK
英文名称： ISOPORE POLYCARB .4UM BK PL 25MM 100/PK
型号:null    抗体货号： HTBP02500
价格:请致电：010-57128832,18610462672
品牌: 德国    产品商标: merck-millipore

ions.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NAP1L2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
NAP1L2,脑特异性蛋白BPX抗体PubMedPubMed
产品介绍background:
Proper nucleosome assembly is critical for compacting DNA into chromatin. In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family. NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied. The remaining three family members, NAP1L2, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed. NAP1L2 (nucleosome assembly protein 1-like 2), also known as BPX (brain specific protein, X-linked), is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions. NAP1L2 binds to chromatin and interacts with Histones H3 and H4. The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons.

Function:
NAP1L2 is a member of the nucleosome assembly protein (NAP) family.

Subcellular Location:
Nuclear

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:
UniProtKB/Swiss-Prot: Q9ULW6.1

NAP1L2,脑特异性蛋白BPX抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

pe isoforms (neurexin-1-alpha) interact (via laminin G-like domain 2 and/or laminin G-like domain 6) with DAG1 (via alpha-dystroglycan chain). Alpha-type isoforms interact with alpha-latroxin from spider venom. The cytoplasmic C-terminal region binds to CASK, CASKIN1 and APBA1. Interacts with SYT13 and SYTL1 (By similarity).

Neurexin 1,轴突蛋白1(Neurexin 1α)抗体Subcellular Location:
Membrane.

Tissue Specificity:
Heart and brain.

Post-translational modifications:
N-glycosylated (By similarity).
O-glycosylated (By similarity).

Similarity:
Belongs to the neurexin family.
Contains 3 EGF-like domains.
Contains 6 laminin G-like domains.

Database links:
UniProtKB/Swiss-Prot: Q9ULB1.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; 
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
Incubation: Anti-Neurexin-1 Polyclonal Antibody, Unconjugated(HZ-11036R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining