SOX22,核转录因子SOX22抗体

产品编号HZ-11207R
英文名称SOX22
中文名称核转录因子SOX22抗体
别 名SOX12; Homo sapiens SRY (sex determining region Y) box 12; Protein SOX-22; SOX 12; SOX 12 protein; SOX 22; SOX 22 protein; sox12; SOX12 protein; SOX12_HUMAN; SOX22 protein; SRY (sex determining region Y) box 12; SRY (sex determining region Y) box 22; SRY box 12; SRY box 22; SRY related HMG box gene 22; Transcription factor Sox-12.
说 明 书0.1ml 0.2ml
研究领域
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow,
SOX22,核转录因子SOX22抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SOX22
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SOX22,核转录因子SOX22抗体PubMedPubMed
产品介绍background:
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
Binds to the sequence 5'-AACAAT-3' (By similarity).

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive.

Similarity:
Contains 1 HMG box DNA-binding domain.

SOX22,核转录因子SOX22抗体Database links:
Entrez Gene: 6666 Human
Entrez Gene: 20667 Mouse
Omim: 601947 Human
SwissProt: O15370 Human
SwissProt: Q04890 Mouse
Unigene: 43627 Human
Unigene: 712815 Human
Unigene: 28424 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.