Cystatin A,胱抑素A/半胱氨酸蛋白酶抑制剂A抗体

产品编号HZ-4937R
英文名称Cystatin A
中文名称胱抑素A/半胱氨酸蛋白酶抑制剂A抗体
别 名AREI; CSTA; CSTA protein; Cystatin A; Cystatin AS; Cystatin-A; Cystatin-AS; CystatinA; CYTA_RAT; Stefin A; Stefin A1; Stefin-A; StefinA; STF 1; STF1; STFA.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 信号转导 细胞凋亡 细胞类型标志物 细胞骨架 肿瘤细胞生物标志物 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, Rabbit,
Cystatin A,胱抑素A/半胱氨酸蛋白酶抑制剂A抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from rat Cystatin A
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cystatin A,胱抑素A/半胱氨酸蛋白酶抑制剂A抗体PubMedPubMed
产品介绍background:
Cystatin A and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. Cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.

Function:
This is an intracellular thiol proteinase inhibitor.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in the skin throughout the epidermis.

Post-translational modifications:

Similarity:
Belongs to the cystatin family.

Cystatin A,胱抑素A/半胱氨酸蛋白酶抑制剂A抗体Database links:
Entrez Gene: 1475 Human
Entrez Gene: 209294 Mouse
Omim: 184600 Human
SwissProt: P01040 Human
SwissProt: P56567 Mouse
Unigene: 518198 Human
Unigene: 300592 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.