BMP11,骨形态发生蛋白11抗体

产品编号HZ-7076R
英文名称BMP11
中文名称骨形态发生蛋白11抗体
别 名BMP 11 BMP11; Bone morphogenetic protein 11; GDF 11; Growth differentiation factor 11; GDF11_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 生长因子和*** 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Chicken, Pig, Cow, Rabbit, Sheep,
BMP11,骨形态发生蛋白11抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BMP11
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BMP11,骨形态发生蛋白11抗体PubMedPubMed
产品介绍background:
BMP11 is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. BMP11 is a secreted signal that acts globally to specify positional identity along the anterior/ posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.

Function:
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted (Probable).

Post-translational modifications:

BMP11,骨形态发生蛋白11抗体DISEASE:

Similarity:
Belongs to the TGF-beta family.

Database links:
UniProtKB/Swiss-Prot: O95390.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.