ARP1B/PC3,肌动蛋白相关蛋白1B抗体

产品编号HZ-19902R
英文名称ARP1B/PC3
中文名称肌动蛋白相关蛋白1B抗体
别 名Actin related protein 1B; Actin-related protein 1B; ACTR 1B; ACTR1B; ACTY_HUMAN; ARP 1B; ARP1 actin related protein 1 homolog B; ARP1 actin related protein 1 homolog B centractin beta (yeast); ARP1 actin related protein 1 homolog B centractin beta; ARP1 actin related protein 1 yeast homolog B centractin beta; ARP1 yeast homolog B; ARP1B; Beta centractin; Beta-centractin; Centractin beta (Yeast); Centractin beta; CTRN 2; CTRN2; PC 3; PC3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 结合蛋白 细胞骨架
抗体来源Rabbit
克隆类型Polyclonal
ARP1B/PC3,肌动蛋白相关蛋白1B抗体交叉反应Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ARP1B
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ARP1B/PC3,肌动蛋白相关蛋白1B抗体PubMedPubMed
产品介绍background:
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]

Function:
Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.

Subunit:

Subcellular Location:
Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome.

Tissue Specificity:

Similarity:
Belongs to the actin family. ARP1 subfamily.

Gene ID:
10120

ARP1B/PC3,肌动蛋白相关蛋白1B抗体Database links:
Entrez Gene: 100125305 Cow
Entrez Gene: 611680 Dog
Entrez Gene: 10120 Human
Entrez Gene: 226977 Mouse
Entrez Gene: 316333 Rat
Omim: 605144 Human
SwissProt: A4IFE3 Cow
SwissProt: P42025 Human
SwissProt: Q8R5C5 Mouse
Unigene: 98791 Human
Unigene: 28521 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.