BLCAP,膀胱癌相关蛋白BLCAP抗体

产品编号HZ-18477R
英文名称BLCAP
中文名称膀胱癌相关蛋白BLCAP抗体
别 名Bc10; Bladder cancer 10 kDa protein; Bladder cancer related protein (10kD); Bladder cancer-associated protein; BLCAP; BLCAP_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
BLCAP,膀胱癌相关蛋白BLCAP抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量10kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BLCAP
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BLCAP,膀胱癌相关蛋白BLCAP抗体PubMedPubMed
产品介绍background:
This gene encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis. The first intron of this gene contains the neuronatin gene, which is imprinted and only expressed from the paternal allele. This gene is imprinted in brain where it is differentially expressed from different promoters. Transcription from the upstream promoter occurs preferentially on the maternal allele, and transcripts are preferentially expressed from the downstream promoter on the paternal allele. Alternative promoters and alternative splicing result in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2009]

Function:
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas.

Similarity:
Belongs to the BLCAP family.

Gene ID:
10904

BLCAP,膀胱癌相关蛋白BLCAP抗体Database links:
Entrez Gene: 10904 Human
Entrez Gene: 53619 Mouse
Entrez Gene: 171113 Rat
Omim: 613110 Human
SwissProt: P62952 Human
SwissProt: P62951 Mouse
SwissProt: P62950 Rat
Unigene: 472651 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.