C1orf69,1号染色体开放阅读框69抗体
英文名称: Anti-C1orf69 antibody
型号:null    抗体货号: HZ-15075R
价格:请致电:010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

C1orf69,1号染色体开放阅读框69抗体

产品编号HZ-15075R
英文名称C1orf69
中文名称1号染色体开放阅读框69抗体
别 名C1orf69; CA069_HUMAN; CAF17_HUMAN; FLJ12734; FLJ13849; IBA57; IBA57 iron sulfur cluster assembly homolog; IBA57 iron sulfur cluster assembly homolog (S. cerevisiae); Iron sulfur cluster assembly factor for biotin synthase and aconitase like; Iron-sulfur cluster assembly factor homolog; mitochondrial; Mitochondrial proteins with a mass of 57kDa; Putative transferase C1orf69; Putative transferase C1orf69 mitochondrial; Putative transferase CAF17, mitochondrial.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig,
C1orf69,1号染色体开放阅读框69抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human C1orf69
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
C1orf69,1号染色体开放阅读框69抗体PubMedPubMed
产品介绍background:
Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Function:
Required for normal heme biosynthesis (By similarity).

Subcellular Location:
Mitochondrion (Potential).

C1orf69,1号染色体开放阅读框69抗体Similarity:
Belongs to the GcvT family. CAF17 subfamily.

Database links:
UniProtKB/Swiss-Prot: Q5T440.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.