CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体
英文名称: Anti-CTAGE4 antibody
型号:null    抗体货号: HZ-8193R
价格:请致电:010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体

产品编号HZ-8193R
英文名称CTAGE4
中文名称皮肤T细胞淋巴瘤相关抗原4抗体
别 名CTAGE family, member 4; CTAGE4; CTGE4_HUMAN antibody Cutaneous T-cell lymphoma-associated antigen 4; Protein cTAGE-4.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 t-淋巴细胞 肿瘤细胞生物标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量88kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from huamn CTAGE4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体PubMedPubMed
产品介绍background:
Tumor-associated antigen.
Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

Function:
Tumor-associated antigen.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

Similarity:
Belongs to the cTAGE family.

Gene ID:
100128553

CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体Database links:
Entrez Gene: 100128553 Human
Omim: 608910 Human
SwissProt: Q8IX94 Human
Unigene: 645204 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

鞍酌窧抗体Database links:
Entrez Gene: 1508 Human
Entrez Gene: 13030 Mouse
Entrez Gene: 64529 Rat
Omim: 116810 Human
SwissProt: P07858 Human
SwissProt: P10605 Mouse
SwissProt: P00787 Rat
Unigene: 520898 Human
Unigene: 236553 Mouse
Unigene: 472420 Mouse
Unigene: 100909 Rat


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成与降解(Synthesis and Degradation)
组织蛋白酶B(CB) 参与肿瘤的侵袭转移过程。可促进肿瘤血管的增生,增强肿瘤细胞的运动能力.组织蛋白酶B转录以及表达水平的高低与肿瘤预后呈正相关。
cathepsin B属于半胱氨酸蛋白酶,与人体的多种生理、病理过程密切相关.组织蛋白酶B (cathepsin B,CB)主要存在于溶酶体中, 发挥其生理状态下的蛋白水解作用.但在某些特定条件下, CB在胞外间质中有时也可以检测到.
目前,有学者将CB用于阿尔茨海默病(AD)方面的研究。