gamma crystallin S,γ晶状体蛋白S/γS-crystallin抗体

产品编号HZ-9585R
英文名称gamma crystallin S
中文名称γ晶状体蛋白S/γS-crystallin抗体
别 名rncat; AI327013; Beta-crystallin S; CRBS_HUMAN; CRYG8; crygs; Crystallin, gamma 8; Crystallin, gamma polypeptide 8; Crystallin, gamma S; Gamma crystallin S; Gamma S crystallin; Gamma-crystallin S; Gamma-S-crystallin; Opacity due to poor secondary fiber cell junction; recessive nuclear cataract; Opj.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
gamma crystallin S,γ晶状体蛋白S/γS-crystallin抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量20kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human gamma crystallin S(121-168aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
gamma crystallin S,γ晶状体蛋白S/γS-crystallin抗体PubMedPubMed
产品介绍background:
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.

Function:
Crystallins are the dominant structural components of the vertebrate eye lens.

Subunit:
Monomer.

Subcellular Location:
Has a two-domain beta-structure, folded into four very similar Greek key motifs.

Post-translational modifications:

Similarity:
Belongs to the beta/gamma-crystallin family.
Contains 4 beta/gamma crystallin 'Greek key' domains.

Database links:
Entrez Gene: 1427 Human
Entrez Gene: 12970 Mouse
Entrez Gene: 689897 Rat
Omim: 123730 Human
SwissProt: P06504 Cow
SwissProt: P22914 Human
SwissProt: O35486 Mouse
SwissProt: P0C5E9 Rat
Unigene: 376209 Human
Unigene: 6253 Mouse
Unigene: 198271 Rat

gamma crystallin S,γ晶状体蛋白S/γS-crystallin抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.