Salmonella typhimurium O,伤寒沙门氏菌体蛋白O抗原抗体

产品编号HZ-8660R
英文名称Salmonella typhimurium O
中文名称伤寒沙门氏菌体蛋白O抗原抗体
别 名Silent protein UshA(0); USHA_SALTY.
说 明 书0.1ml 0.2ml
研究领域细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Mouse, SalnellatyphimuriumO
Salmonella typhimurium O,伤寒沙门氏菌体蛋白O抗原抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量58kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原whole cell protein of Salmonella typhimurium O
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Salmonella typhimurium O,伤寒沙门氏菌体蛋白O抗原抗体PubMedPubMed
产品介绍background:
The genus Salmonella is a member of the family Enterobacteriaceae. The genus is composed of Gram-negative bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major antigens; the "H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram-negative bacteria. This LPS is composed of an "O" polysaccharide ("O" antigen) an "R" core and the endotoxic inner "Lipid A". Endotoxins evoke fever and can activate complement, kinin and clotting factors. Until recently the most common cause of food poisoning by Salmonella species was due to S. Typhimurium. As its name suggests, it causes a typhoid-like disease in mice. In humans S. Typhimurium does not cause as severe disease as S. Typhi, and is not normally fatal. The disease is characterized by diarrhea, abdominal cramps, vomiting and nausea, and generally lasts up to 7 days.

Subcellular Location:
Periplasm (By similarity).

Similarity:
Belongs to the 5'-nucleotidase family.

Database links:
UniProtKB/Swiss-Prot: P06196.2

Salmonella typhimurium O,伤寒沙门氏菌体蛋白O抗原抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

伤寒沙门氏菌 Salmonella typhimurium 　　属于沙门氏菌B群。O抗原有1，4，5，12，H抗原单相为1，双相为1，2。它是引起食物中毒而发生炎症的有名的细菌，但通过P22噬菌体转导、溶原化变换以及组氨酸操纵子等性状出现的调节机制的分析，也成为了促进微生物遗传学发展的一种重要的细菌。