NYS48,NYS48蛋白抗体

产品编号HZ-9320R
英文名称NYS48
中文名称NYS48蛋白抗体
别 名HAUS augmin like complex subunit 8; Hec1 interacting and centrosome associated 1; HEC1/NDC80 interacting centrosome associated protein 1; HICE 1; HICE1; MGC20533; NY SAR 48; Sarcoma antigen NY SAR 48; HAUS8_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 细胞周期蛋白 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse,
NYS48,NYS48蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NYS48
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
NYS48,NYS48蛋白抗体PubMedPubMed
产品介绍background:
NYS48 belongs to the HAUS8 family. It is required for stabilizing spindle integrity and chromosomal integrity.

Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Subunit:
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Associates with microtubules. The interaction with microtubules is strong during mitosis, while it is weak or absent during interphase. It is unclear whether this interaction is direct or indirect.

Subcellular Location:
Cytoplasm, cytoskeleton, Microtubule.

Similarity:
Belongs to the HAUS8 family.

Gene ID:
93323

NYS48,NYS48蛋白抗体Database links:
Entrez Gene: 93323 Human
Omim: 613434 Human
SwissProt: Q9BT25 Human
Unigene: 404088 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.