CENPBD1,CENPBD1蛋白抗体

产品编号HZ-13833R
英文名称CENPBD1
中文名称CENPBD1蛋白抗体
别 名CENP1_HUMAN; CENPB DNA binding domains containing 1; CENPB DNA-binding domain-containing protein 1; CENPBD1; FLJ23771; FLJ31569; MGC13198; MGC16385.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 神经生物学 结合蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
CENPBD1,CENPBD1蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量21kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CENPBD1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CENPBD1,CENPBD1蛋白抗体PubMedPubMed
产品介绍background:
CENPBD1 is a 187 amino acid nuclear protein that contains one HTH CENPB-type DNA-binding domain and a HTH psq-type DNA-binding domain. The gene encoding CENPBD1 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 HTH CENPB-type DNA-binding domain.
Contains 1 HTH psq-type DNA-binding domain.

Gene ID:
92806

Database links:
Entrez Gene: 92806 Human
SwissProt: B2RD01 Human
Unigene: 513832 Human

CENPBD1,CENPBD1蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.