ESM1,内皮细胞特异性分子1抗体

产品编号HZ-3615R
英文名称ESM1
中文名称内皮细胞特异性分子1抗体
别 名Endocan; Endothelial cell specific molecule 1; ESM 1; ESM-1; ESM 1 secretory protein; ESM1 secretory protein; ESM1_HUMAN; Endothelial cell-specific molecule 1.
说 明 书0.1ml 0.2ml
研究领域心血管 免疫学 细胞粘附分子 内皮细胞
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse,
ESM1,内皮细胞特异性分子1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量20kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ESM1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ESM1,内皮细胞特异性分子1抗体PubMedPubMed
产品介绍background:
ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

Function:
May have potent implications in lung endothelial cell-leukocyte interactions.

Subunit:
Monomer.

Subcellular Location:
Secreted. Peroxisome.

Tissue Specificity:
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.

Post-translational modifications:
May contain intrachain disulfide bonds.

Similarity:
Contains 1 IGFBP N-terminal domain.

ESM1,内皮细胞特异性分子1抗体Database links:
UniProtKB/Swiss-Prot: Q9NQ30.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.