GNL1,鸟嘌呤核苷酸结合蛋白1抗体
英文名称: Anti-GNL1 antibody
型号:null    抗体货号: HZ-8040R
价格:请致电:010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

GNL1,鸟嘌呤核苷酸结合蛋白1抗体

产品编号HZ-8040R
英文名称GNL1
中文名称鸟嘌呤核苷酸结合蛋白1抗体
别 名Gnl1; GNL1_HUMAN; GTP binding protein HSR1; GTP-binding protein HSR1; Guanine nucleotide binding protein like 1; Guanine nucleotide-binding protein-like 1; HSR1; HSR1 GTP binding protein.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Monkey, y
GNL1,鸟嘌呤核苷酸结合蛋白1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量69kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human GNL1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
GNL1,鸟嘌呤核苷酸结合蛋白1抗体PubMedPubMed
产品介绍background:
The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008].

Function:
Possible regulatory or functional link with the histocompatibility cluster.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the MMR1/HSR1 GTP-binding protein family.
Contains 1 G (guanine nucleotide-binding) domain.

Database links:
UniProtKB/Swiss-Prot: P36915.2

GNL1,鸟嘌呤核苷酸结合蛋白1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

Function:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).

Subunit:
Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration. Interacts with TIPIN.

Peroxiredoxin 2,硫氧还蛋白过氧化物酶Ⅱ/巯基抗氧化蛋白抗体Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the AhpC/TSA family.
Contains 1 thioredoxin domain.

Gene ID:
7001

Database links:
Entrez Gene: 286793 Cow
Entrez Gene: 7001 Human
Entrez Gene: 21672 Mouse
Entrez Gene: 29338 Rat
Omim: 600538 Human
SwissProt: Q9BGI3 Cow
SwissProt: P32119 Human
SwissProt: Q61171 Mouse
SwissProt: P35704 Rat
Unigene: 432121 Human
Unigene: 347009 Mouse
Unigene: 393373 Mouse
Unigene: 2511 Rat

Peroxiredoxin 2,硫氧还蛋白过氧化物酶Ⅱ/巯基抗氧化蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.